Inthe same line, De Gottardi et al. showed that (1) PPARγ expression wassignificantly lower in genotype 3 compared with genotype 1 HCV infection and (2) steatosis wasassociated to decreased levels of PPARγ in genotype 1 HCV infection.In this study, there was no significant relationship between PPARs mRNA levelsand liver activity or fibrosis. This evidence concerns the gene PPARG and steatosis.