CDKN2A and ischemic stroke: Recent human genome-wide association studies (GWAS) have shown that SNPs with high minor allele frequencies near the INK4/ARF (CDKN2A/B) tumor suppressor locus on chromosome 9p21 correlate with risk of atherosclerotic diseases (coronary artery disease (CAD) [1], [2], [3], [4], [5], ischemic stroke [6], [7], and abdominal aortic aneurysm[6]) and type 2 diabetes mellitus (T2DM) [8], [9], [10].