A positive association was found between ESAT6 induced IFNγ and CXCL9 in all TB patients indicating that this balance may play a predictive role in the Th1-like cytokine balance required for protection against M. tuberculosis. However, as association between the macrophage activating CCL2 and the T cell activation IFNγ and CXCL9 was only found in LNTB patients. Here, IFNG is linked to tuberculosis.