Multiple literatures have reported that abnormal elevation rates of biomarkers, 34.6% for carcinoembryonic antigen (CEA), 30.8% for carbohydrate antigen 19-9 (CA19-9) and 30.8% for cancer antigen 125 (CA125) have been observed in cases of bone metastasis [3]. This evidence concerns the gene CEACAM5 and bone metastasis.