The BST2 mRNA was significantly increased (P < 0.01) in the bone metastatic breast cancer cell lines, MDA-231BO compared to the normal breast cell line, MCF-10A, and the non-bone metastatic breast cancer cell lines, HTB-121, UACC812, MCF-7, T47D, MDA-468, BC-701 and MDA-231 by real time RT-PCR (Figure 2). Here, BST2 is linked to breast cancer.