In fact, VEGF-A is highly expressed in many malignant tumors, including lung cancer [30], [31], [32], and the expression of VEGF-A is associated with poor prognosis [33], [34] and the presence of lymph node metastasis [35], raising the possibility that the biological roles of FLJ10540 and VEGF-A might be functionally linked in lung adenocarcinoma. This evidence concerns the gene VEGFA and cancer.