The list includes eight genes known to be modulated by interferon levels in human: CXCL16, IFI44, IFNAR1, IFNAR2, IFNGR2, ISG15, MX1, and STAT2. Specific enrichment of immune-related genes in group F probably reflects the presence of lymphocytes infiltrating both "benign and intermediate" and "malignant" tumor classes as compared to their normal tissue counterparts. This evidence concerns the gene ISG15 and neoplasm.