ALB and Renal insufficiency: In contrast, a recent investigation of 421 Asian Indian type 2 diabetics did find an association between the AGT 235 T-allele and renal insufficiency (defined as plasma creatinine ≥ 3 mg/dl and/or urinary albumin excretion rate > 200 mcg/min) (OR 2.68, 95%CI 2.01 to 3.57) [36].