The interaction between SDF-1α and CXCR4 can elicit a direct chemo-attractive action on breast cancer cells [7], [8] and CXCR4 expression currently used in conjunction with CD133 to define metastatic stem cells [9] suggesting that its pro-metastatic action could broadly apply to metastatic cancer including cervical carcinoma. The gene discussed is CXCR4; the disease is breast cancer.