On bivariate analysis, nonadherence to primary PCP prophylaxis was associated with year of SHAS interview, illicit drug use in the past year, current risk for alcohol abuse, description of mental health as “not good” for ≥1 day in the past month, most recent CD4 count <200 cells/μL, most recent HIV viral load >5,000 copies/mL, and nonadherence to ART in the past month (Table 1). The gene discussed is CD4; the disease is alcohol abuse.