This lateral hypothalamic abnormality would be expected to affect the function of most of the pituitary axes (as shown in other neurodegenerative diseases where neuroendocrine alterations occur [8]), potentially modifying the basal levels of GH, TSH, ACTH, LH, FSH, and prolactin, at least at late in the course of HD. Here, BRD2 is linked to Huntington disease.