The shortest BMCC1 isoform 4 (BMCC1-4/BNIPXL) may have pro-apoptotic affects [24] but this has not been tested in PCa and the role of the much longer BMCC1 isoform 1 (BMCC1-1) has yet to be investigated. The gene discussed is PRUNE2; the disease is posterior cortical atrophy.