DDB1 and neoplasm: A number of genes which have been previously observed to be over-expressed in tumours (Mycs, Clu)[37], tumor suppressors (Patched, Ptch), or otherwise involved in metastasis or DNA repair: bikunin (Ambp)[38], ornithine decarboxylase gene (Odc), Trefoil factor 1 (Tff1)[39], insulin like growth factor (Igf2) [40] and DNA repair protein 1 (Ddb1), were also differentially expressed in NS398 treated infected mice (Figure 3).