(3) "Third, the cloning and characterization of the chromosomal breakpoints that are characteristic of follicular lymphomas, and some diffuse large B-cell lymphomas have shown a juxtaposition of the BCL2 oncogene to enhancer elements in the immunoglobulin heave-chain locus, resulting in deregulation of BCL2 [38]." An alternative explanation is that these chromosomal breakpoints occur after cancer initiation caused by disruption of morphostats and their frequency increases due to selection after the carcinogenesis process is underway. The gene discussed is BCL2; the disease is cancer.