Together with CD133, we also evaluated the expression levels of several cancer stem-cell genes that have recently been shown to be correlated with the aggressiveness of solid tumors; as shown in Text S1, Figure S5 (A–D) and table S3, the expression of these genes is in agreement with an overall reduction in the ‘stemness’ phenotype of Daoy cells treated with N-[N-(3,5-difluorophenacetyl)-l-alanyl]-S-phenylglycine t-butylester (DAPT). The gene discussed is PROM1; the disease is cancer.