CHRNA3 and chronic obstructive pulmonary disease: These results further confirmed the association of two SNPs at the CHRNA3/5 locus with COPD (p = 2.5×10−3, OR = 1.43, combined p value: 1.48×10−10 for rs8034191 and p = 0.017, OR = 1.32, combined p value 5.74×10−10 for rs1051730).