As a result, ERBB2-positive breast cancer cells contain significantly higher amounts of cellular fats, as compared with other breast cancer cell lines or normal cells, because of concomitant overexpression of NR1D1 and PBP genes (Kourtidis A, Carkner RD, Eifert C, Brosnan MJ, Conklin DS; unpublished data) [2]. The gene discussed is NR1D1; the disease is breast carcinoma.