We originally established a link between FOXM1 and tumourigenesis when we demonstrated that FOXM1 was a downstream target of Gli1 in basal cell carcinoma (BCC) and showed that of the three known alternatively spliced isoforms (FOXM1A, B and C), FOXM1B isoform was overexpressed in BCCs [5]. The gene discussed is FOXM1; the disease is basal cell carcinoma.