As before, the endogenous levels of FOXM1 protein in vivo (Fig. 1D–J), and in vitro (Fig. 2, Fig. S1) and the endogenous FOXM1B mRNA in vitro, were significantly upregulated in premalignant and HNSCC cells (Fig. 7C). This evidence concerns the gene FOXM1 and head and neck squamous cell carcinoma.