qPCR results showed that a number of known FOXM1B target genes such as CENPF, CENPA, NEK2 and cyclin B1 (CCNB1) were significantly upregulated in UK1 cells compared to NHOK1 (Fig. 2F) showing that FOXM1B in HNSCC cells was transcriptionally active. The gene discussed is CCNB1; the disease is head and neck squamous cell carcinoma.