IL2 and inflammatory response: In contrast, when IL2:anti-IL-2 complexes were administered both before and after allergenic stimulation, a remarkable increase in Treg counts was observed along with an increase in mRNA and IL-10 levels in lung tissue; in addition, subjects displayed decreased pulmonary pathologic findings (mucus secretion, airway inflammation and hyper-responsiveness), corroborating a similar report by Boyman et al. [49].