Interestingly, mutation of the human gene Foxp3, an ortholog of the gene mutated in scurfy mice (Foxp3) was also the cause for human immunodysregulation polyendocrinopathy enteropathy X-linked syndrome (IPEX), another sex-linked autoimmune syndrome[7]. The gene discussed is FOXP3; the disease is immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome.