A lower expression of PPARγ1 in the proximal tubules,which are derived from the metanephric tissue, has been indicated in the ratkidney [56] while in mesangial cells and podocytes of the kidney capsules PPARγ is upregulated only underpathological conditions as chronic hyperglycemia or glomerulonephritis [10, 12–15]. The gene discussed is PPARG; the disease is glomerulonephritis.