The beneficial effect could be due to the synergistic effect of a upregulation in antioxidant Bcl-2 and HSP-70 protein, a suppression of endothelial ICAM-1 protein expression, and a reduction in leucocyte and platelet adhesion, consequently leading to the delay of FeCl3 induced thrombus formation in the vascular endothelium of HF fed hamsters. Here, BCL2 is linked to hydrops fetalis.