Examples include stearoyl-CoA desaturase 5 that converts fatty acids into monounsaturated forms in the endoplasmic reticulum and involved in dyslipidemia, the ubiquinol-cytochrome c reductase involved in the mitochondrial respiratory chain, the DNA recombination repair protein RAD51, the neuronal thread protein (AD7C-NTP), which is a extracellular protein involved in apoptosis, and the gene for Mediterranean fever (MEFV) which is involved in regulation of transcription and inflammatory response. The gene discussed is MEFV; the disease is metabolic syndrome.