We compared AML patients (Additional File 1) with wild type (2/7, mean survival 49 months, 28 and >69 months respectively) and ITD FLT3 (5/7, mean survival 8 months, range 0–28), and found that at pretreatment only 11 genes differed with false discovery rate of zero (0). The gene discussed is FLT3; the disease is acute myeloid leukemia.