ADIPOQ and adiponectin deficiency: Many cross-sectional studies have demonstrated that hypoadiponectinemia is indeed associated with the prevalence of coronary heart disease.2,12–19 However, because a commercially available method for measuring adiponectin has only recently been introduced, there are still a limited number of prospective studies of the longitudinal relationship between adiponectin level and the incidence of myocardial infarction.