In this context, DC-SIGN has been shown to be an important receptor of HTLV-1, Ebola virus, cytomegalovirus, dengue virus and other agents of infectious disease (Alvarez et al., 2002; Halary et al., 2002; Tailleux et al., 2003; Tassaneetrithep et al., 2003). Here, CD209 is linked to infectious disease.