As a result, the tissues expressing ARSI were, in order from the top, placenta (7 ESTs), retinoic acid-treated embryonic stem cell (6), retinoic acid-treated NT2 embryonic carcinoma cell line (3), colon tumor (3), fetal eyes (3), and lens (3), suggesting that ARSI is preferentially expressed in placenta, embryonic cell, and eye. The gene discussed is ARSI; the disease is embryonal carcinoma.