Though in previous studies, populations at high risk of developing HCC in HCV infected patients include those of older age, male sex, non-response to initial IFN (25), in the present study, the average age of patients in both the HCC and non-HCC group was almost same (61.5 ± 7.1: 60.2 ± 9.1) years and there was no male predominancy in either group. Here, IFNA1 is linked to hepatocellular carcinoma.