The samples included in this analysis were representative of a total number of 70 tissue samples (30 IPF, 20 controls and 20 COP) used for TMA construction and immunohistochemistry semi-quantitative analysis which further corroborated ING4 down-regulation in IPF patients compared to controls and COP subjects, on a protein level as well (Figure 4). The gene discussed is ING4; the disease is idiopathic interstitial pneumonia.