Regarding FDFT1 we failed to demonstrate an association between the rs7001819 C-allele and measures of obesity, both when investigating quantitative phenotypes including BMI and waist circumference and dichotomous BMI cut-offs of overweight, obesity and morbid obesity, consistent with the fact that no association with fat mass was observed in the initial study [16]. Here, FDFT1 is linked to obesity due to melanocortin 4 receptor deficiency.