CTNNBL1 and obesity due to melanocortin 4 receptor deficiency: When combining our data on obese individuals with the French Caucasian morbid obesity data used for replication by Liu et al. [16], in a meta-analysis, a significant association is also observed with a combined OR of 1.17 [1.04–1.31], suggesting that CTNNBL1 is likely be a true obesity gene conferring risk of developing both obesity and morbid obesity.