Because depletion of proteins of the gamma-tubulin complex sensitizes p53-mutated cells derived from non-small cell lung cancer for the treatment with the chemotherapeutic agent paclitaxel [13], we wanted to confirm that specific depletion of NEDD1 had a similar effect in HeLa and in HCT116 cells with and without p53 (Figure 5A, Figure 5B, Figure 5C, Figure 5D, Figure 5E, Figure 5F, Figure 5G). The gene discussed is TP53; the disease is non-small cell lung carcinoma.