However, it has to be considered that a low concentration measured in cell supernatants can be dramatically high for a portion of the cell membrane and that the LNCaP cell line used by us represents only one of the multiple clones composing the prostate cancer cell population, thus emphasizing the importance that the synergic activity of IL-6 and CCL5 on LNCaP cells proliferation described by us may have in an “vivo” microenvironment. Here, IL6 is linked to Familial prostate cancer.