In this study, we describe the biological activity of 8-(1-Hydroxy-ethyl)-2-methoxy-3-(4-methoxy-benzyloxy)-benzo[c]chromen-6-one (P529), a recently discovered drug that targets Akt, which has been shown to inhibit tumour angiogenesis, vascular permeability, and tumour growth, in a mouse model of glioblastoma (Xue et al, 2008). This evidence concerns the gene AKT1 and glioblastoma.