Similarly, two other studies in paired NSCLC tumours showed a discordance of 32 and 27% regarding the EGFR gene copy number (Italiano et al, 2006; Bozzetti et al, 2008), whereas another study including six NSCLC patients of Asian ethnicity reported a 100% concordance in regard to EGFR mutation status (Matsumoto et al, 2006). The gene discussed is EGFR; the disease is neoplasm.