MET and neoplasm: Dysregulation of the MET–HGF signalling axis upregulates diverse tumour cell functions, including cell proliferation, survival, cell scattering and motility, epithelial-mesenchymal transition, angiogenesis, invasion, and metastasis (Corso et al, 2005; Dietrich et al, 2005; Ma et al, 2005a; Peruzzi and Bottaro, 2006).