Inoculation of HCVcc on SK-Hep1-CLDN1 and SK-Hep1-CLDN1-SR-BI cellsyielded strong RT-qPCR signals at 4 hr post-infection, indicating binding and/orcapture of viral particles [9], that progressively declined with10–30 fold loss at 12 hr (Figure 2A). The gene discussed is CLDN1; the disease is infection.