An interferon gene signature was also present in the profiles derived from the tumor epithelium of the ER-positive tumors (e.g., STAT1, IFIT1, IFIH1, IFI27, ISG15, OAS1, OAS3, OASL; Table S2) and ER-negative tumors (e.g., HLA-DQA1 and HLA-DQB1; Table S3). This evidence concerns the gene IFI27 and neoplasm.