HIF1A and gastric adenocarcinoma: Several immunhistochemical studies showed that HIF-1α is overexpressed in gastrointestinal stromal tumours of the stomach (Takahashi et al, 2003; Chen et al, 2005) and gastric adenocarcinomas but absent in normal gastric mucosa (Mizokami et al, 2006; Sumiyoshi et al, 2006; Urano et al, 2006; Griffiths et al, 2007).