VEGFC and metastatic malignant neoplasm in the lymph nodes: Namely, ptLVD was higher in stage III a patients than in stage I and II (P < 0.01), in LVI positive than in LVI negative (P = 0.004), in lymph node metastasis than in lymph node negative (P < 0.01), in VEGF-C positive than in VEGF-C negative (P < 0.01) in high Ki67% than in low Ki67%.