IFNG and neoplasm: To determine whether intratumoral administration of Ad-IFNγ could achieve localized sustained expression of IFNγ, we sought to characterize the biodistribution of the adenoviral vector and transgene expression in the tumor, blood, liver, kidney, heart, brain, spleen, and lung at days 1, 2, 3, 5, 7, 14, and 21 after injection.