AFP and neoplasm: High Edmondson grade (grade I vs II, P = 0.020; grade I vs III-IV, P = 0.019), high AFP level (P = 0.0070), large tumor size (P = 0.00012), and high tumor stage (stage I vs II, P = 0.0068; stage I vs III-IV, P = 2.2 × 10-5) were identified as important risk factors for OS (Table 2), whereas high NNMT mRNA level (P = 0.018) and high tumor stage (stage I vs III-IV, P = 0.0049) were identified as important risk factors for DFS (Table 3).