F2 and Disseminated intravascular coagulation: In addition to these highly over-expressed genes, there is modest up-regulation of coagulation factors II, V, and X which should promote coagulation and has been associated with consumptive coagulopathy and disseminated intravascular coagulation (DIC); although DIC has not been associated with Lassa [13] as it has with other hemorrhagic virus infections like Ebola fever [33].