Glial-specific RNAi knock down of pnt reduced Stg expression and completely suppressed dEGFRλ;dp110CAAX neoplasia (Figure 5E–H), demonstrating that Pnt proteins are required for both Stg expression and neoplastic overproliferation in dEGFRλ;dp110CAAX glia. Here, C6orf15 is linked to neoplasm.