It is thus possible that, by sequestering MPs in the adipose tissue, obese patients could have tissue or organ repair impediments and that treatment with anti-adipotaxis agents (like anti-TNF antibodies) could prove a valuable therapeutic approach to improve repair mechanisms in organs like muscle, lung, skin, kidney, etc. Indeed, obese patients (specially those with diabetes) have impaired wound healing regardless of the degree of glucose control and insulin therapy. Here, INS is linked to diabetes mellitus.