MKI67 and infection: Finally, sustained and generalized immune activation (Ki67+) was observed at necropsy (day 45+) in PBMCs, spleen, tonsil, bone marrow, thymus, axillary, iliac, and mesenteric lymph nodes, jejunum, and ileum of PTs but not AGMs (Figure 1D), and markers of inflammation (CXCL9/MIG) were increased in lymph nodes of PTs but not AGMs at early (day 10) as well as late (day 45+) time points after infection, while only slightly increased in colonic mucosal tissue of both species at later time points (Figure S1D).