For patients who achieved an HbA1c < 7.0% without hypoglycaemia, total insulin daily dose was 29.6 ± 14.3 U (0.44 ± 0.21 U/kg) at baseline and 28.8 ± 14.2 U (0.43 ± 0.19 U/kg) at final visit (p = 0.0003). Here, INS is linked to Hypoglycemia.