In the subgroup of well and moderately differentiated (G1/G2) gastric cancer cases, high HSP-90 expression was significantly associated with longer overall survival times (P = 0.036) (Figure 2C), being also identified as an independent prognostic factor in multivariate analysis (P = 0.018), which was not seen in poorly differentiated (G0) gastric cancer cases (P = 0.754). This evidence concerns the gene HSP90AA1 and gastric cancer.