IL6 and pancolitis: Previous studies either evaluated changes in other than the above mentioned cytokines/chemokines like Raddatz et al. [6] who showed a positive correlation between interleukin 6 (IL-6) mRNA transcript levels and CAI in patients with pancolitis or used methods like Northern Blot analysis [7], in situ hybridization [8], ELISA [7,9-12] or immunohistochemistry [8] which are not considered reliable for quantification of mucosal cytokine gene expression.