Median CD4 was 23 cells/μL (IQR 8.5–96) for persons who died of TB (p<0.01 for comparison with patients who did not die), 18 cells/μL (IQR 8–41) for those who died of an HIV-associated condition other than TB (p <0.01), 18 cells/μL (IQR 4–40) for those in whom TB and an HIV-associated cause of death other than TB were equally likely (p<0.01), and 63 cells/μL (IQR 18–112) among persons who died of a non-TB, non-HIV-associated cause (p = 0.18). This evidence concerns the gene CD4 and tuberculosis.