More recently, Barcellos et al. [20], by aligning the protein sequences of HLA-DRB1*1501, *1503, *1701, *0401, *0801, and *0803 with that of HLA-DRB1*140101, *140102, *140103, and *1404 have suggested that the amino acid at position 60 of the HLA-DRB1 protein sequence determines the effect of a HLA-DRB1 allele on MS susceptibility. Here, HLA-DRB1 is linked to myeloid sarcoma.