Strong TGFβ response glioblastomas identified in this study also showed higher expression of many molecules involved in integrin signaling (ACTA2, ACTN1, ACTN4, ARPC4, COL1A1, COL1A2, COL4A1, COL4A2, DIRAS3, FN1, ITGA2, ITGA3, ITGA4, ITGA7, ITGB1, ITGB2, ITGB4, ITGB5, LAMA4, LAMB1, LAMB2, LAMC1, MRCL3, RAP2B, RHOC, RHOJ, RRAS, SHC1, VASP, and ZYX). This evidence concerns the gene RAP2B and glioblastoma.