SERPINE1 and anaplastic astrocytoma: However, SERPINE1 expression was significantly associated with the following histological types: glioblastoma (GBM), anaplastic astrocytoma (Astro), anaplastic oligodendroglioma (Oligo) and mixed glioma, anaplastic oligoastrocytoma (Mix)(p < 1.52 × 10-5), as well as grades (III and IV) (p < 7.87 × 10-6).