Strong TGFβ response glioblastomas identified in this study also showed higher expression of many molecules involved in integrin signaling (ACTA2, ACTN1, ACTN4, ARPC4, COL1A1, COL1A2, COL4A1, COL4A2, DIRAS3, FN1, ITGA2, ITGA3, ITGA4, ITGA7, ITGB1, ITGB2, ITGB4, ITGB5, LAMA4, LAMB1, LAMB2, LAMC1, MRCL3, RAP2B, RHOC, RHOJ, RRAS, SHC1, VASP, and ZYX). The gene discussed is ACTN1; the disease is glioblastoma.