KRAS and neoplasm: Genes with very similar functional annotations were also regulated in expression studies of KrasG12V-transformed rat embryonic fibroblast (Tchernitsa et al, 2004) in tumours derived from KrasG12V mouse embryonic fibroblasts (Vasseur et al, 2005) and in a human colon adenoma cell line constitutive active Kras due to a mutation in codon 12 (Roberts et al, 2006).